通用名称
apalutamide [ AP-a-LOOT-a-mide ]英文名称
Apalutamide汉语拼音
N/A药品类型
oral tablet (240 mg; 60 mg)处方类型
N/A医保类型
N/A- What is apalutamide?
- Apalutamide side effects
- Warnings
- Before taking this medicine
- How should I take apalutamide?
- Dosing information
- What happens if I miss a dose?
- What happens if I overdose?
- What should I avoid while taking apalutamide?
- What other drugs will affect apalutamide?
- Frequently asked questions
-
What is apalutamide?
Apalutamide is to treat prostate cancer that has spread to other parts of the body (metastatic) and still responds to a medical or surgical treatment that lowers testosterone.@@@Apalutamide is also used to treat prostate >cancer that has not spread to other parts of the body, after surgery or other treatments did not work or have stopped working.@@@@@@Apalutamide belongs to a class of medications called androgen receptor inhibitors. It works by blocking the effects of androgen (a male reproductive hormone) to stop the growth and spread of cancer cells.@@@This medicine is not approved for use in women or children.@@@
-
Apalutamide side effects
Get emergency medical help if you have signs of an allergic reaction to apalutamide: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).@@@Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.@@@Apalutamide may cause serious side effects. Call your doctor at once if you have:@@@chest pain, feeling short of breath; a seizure; a fall; or signs of a stroke--sudden numbness or weakness, severe headache, slurred speech, problems with vision or balance.@@@Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.@@@Accidental falls may be more common in older adults who take this medicine. Use caution to avoid falling or accidental injury.@@@Common apalutamide side effects may include:@@@hot flashes; diarrhea, loss of appetite; weight loss; tiredness; falls; rash; joint pain; increased blood pressure; or bone fractures.@@@@@@This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.@@@Apalutamide side effects (more detail)@@@Related/similar drugs estradiol, Premarin, Xtandi, Zytiga, Casodex, Lynparza@@@
-
Warnings
Although apalutamide is not for use by women, this medicine can cause birth defects if a woman is exposed to it during pregnancy.@@@Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical condition, allergies, and all medicines you use.@@@
-
Before taking this medicine
To make sure apalutamide is safe for you, tell your doctor if you have ever had:@@@a head injury or brain tumor; a seizure; a stroke; heart disease, high blood pressure; diabetes; or high cholesterol or triglycerides.@@@Apalutamide can harm an unborn baby if the father is using this medicine.@@@Use birth control if your sex partner is able to get pregnant. Men using apalutamide should use condoms during treatment. Keep using birth control for at least 3 months after your last dose. Tell your doctor right away if a pregnancy occurs.@@@It may be harder for you to get a woman pregnant while you are using this medicine. Do not donate sperm while you are taking apalutamide, and during the 3 months after your last dose.@@@Apalutamide can weaken your bones. You may be more likely to have a broken bone while taking this medicine. Talk with your doctor about ways to keep your bones healthy.@@@Apalutamide pregnancy and breastfeeding warnings (more detail)@@@
-
How should I take apalutamide?
Take apalutamide exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.@@@You may take apalutamide with or without food but take it the same way each time.@@@Apalutamide is usually taken once per day. Follow your doctor's dosing instructions very carefully.@@@You may be given another medication while you are on apalutamide, unless you have had surgery to remove your testicles. Keep using this medicine for as long as your doctor has prescribed.@@@Swallow the tablet whole and do not crush, chew, or break it.@@@Read and carefully follow the instructions provided with this medicine on how to prepare and take apalutamide if you cannot swallow tablets whole. This medicine may also be given through a feeding tube. Ask your doctor or pharmacist if you don't understand these instructions.@@@You may need frequent medical tests and your cancer treatments may be delayed based on the results.@@@Your condition may get worse if you stop using this medicine. Ask your doctor before stopping the medicine.@@@@@@Store at room temperature away from moisture, heat, and light. Keep the medicine in the original container, along with the packet or canister of moisture-absorbing preservative.@@@
-
Dosing information
Usual Adult Dose for Prostate Cancer:@@@240 mg orally once a day Comments: -Patients should receive a gonadotropin-releasing hormone (GnRH) analog concurrently or have had a bilateral orchiectomy. Uses: -For the treatment of metastatic castration-sensitive prostate cancer (mCSPC) -For the treatment of non-metastatic castration-resistant prostate cancer (nmCRPC)@@@Detailed Apalutamide dosage information@@@
-
What happens if I miss a dose?
Take the missed dose on the same day you remember it. Take your next dose at the regular time and stay on your once-daily schedule. Do not take two doses in one day.@@@
-
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.@@@
-
What should I avoid while taking apalutamide?
Apalutamide can cause seizures. Avoid activities that could be dangerous if you have an unexpected seizure.@@@
-
What other drugs will affect apalutamide?
Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.@@@Other drugs may interact with apalutamide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.@@@Apalutamide drug interactions (more detail)@@@
-
Frequently asked questions
How long do you have to take Erleada (apalutamide) for? How effective is Erleada (apalutamide)? What type of prostate cancer is Erleada used to treat?@@@References Erleada Product Label@@@More about apalutamide Check interactions Compare alternatives Reviews (19) Side effects Dosage information During pregnancy Drug class: antiandrogens En español Patient resources Other brands Erleada Professional resources Apalutamide monograph Other brands Erleada Related treatment guides Prostate Cancer@@@